Description

n-Boc-Isonipecotic Acid is a protected derivative of isonipecotic acid, featuring a tert-butoxycarbonyl (Boc) group. This compound is a crucial pharmaceutical intermediate and building block in organic synthesis, valued for its role in constructing complex molecules. It is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide chemistry.
• Chemical Research & Development: Serves as a versatile scaffold for creating novel chemical libraries and exploring structure-activity relationships (SAR).
• Agrochemical Synthesis: Employed in the development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Utilized to synthesize complex ligands for metal catalysis and chiral auxiliaries.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Item	Details
Product Name	n-Boc-Isonipecotic Acid
CAS No.	174316-71-3
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	1-Boc-4-piperidinecarboxylic Acid; 1-(tert-Butoxycarbonyl)piperidine-4-carboxylic Acid; 4-(Boc-amino)piperidine-4-carboxylic Acid; tert-Butyl 4-carboxypiperidine-1-carboxylate; N-Boc-4-piperidinecarboxylic Acid; N-(tert-Butoxycarbonyl)isonipecotic Acid; Boc-Isonipecotic Acid; 1-N-Boc-piperidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our n-Boc-Isonipecotic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.