Description

tert-Butyl 3-Methyl-1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylate is a high-purity, protected heterocyclic building block of significant value in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a reliable, high-quality intermediate to construct complex molecular architectures. It is primarily sought after by the pharmaceutical and agrochemical industries for the development of novel active ingredients, including kinase inhibitors and other biologically relevant molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitor drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that leverage the pyrazolopyridine scaffold.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science: Potential precursor for the synthesis of specialty chemicals and functional materials with specific electronic properties.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and process development projects.

Basic Information

Product Name	tert-Butyl 3-Methyl-1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylate
CAS No.	174180-77-9
Molecular Formula	C13H17N3O2
Molecular Weight	247.29 g/mol
Synonyms	1-Boc-3-methyl-1H-pyrazolo[3,4-b]pyridine; 3-Methyl-1H-pyrazolo[3,4-b]pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 3-methylpyrazolo[3,4-b]pyridine-1-carboxylate; 1H-Pyrazolo[3,4-b]pyridine-1-carboxylic acid, 3-methyl-, 1,1-dimethylethyl ester; 3-Methyl-1-(tert-butoxycarbonyl)-1H-pyrazolo[3,4-b]pyridine; Boc-3-methyl-1H-pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Methyl-1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques like HPLC, NMR, and MS. We adhere to cGMP standards where applicable to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.