Description

4-Iodo-2-Methoxy-6-Trimethylsilanyl-Pyridine-3-Carbaldehyde is a specialized pyridine derivative featuring a reactive aldehyde group and a trimethylsilyl-protecting group. This compound matters as a versatile and high-value chemical building block for advanced organic synthesis, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides with specific modes of action.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and material science.
• Functional Material Development: Employed in the research of organic electronic materials and advanced polymers.
• Cross-Coupling Reactions: The iodine substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Academic & Contract Research: A critical reagent for methodological studies and custom synthesis projects in academic and CRO laboratories.

Basic Information

Product Name	4-Iodo-2-Methoxy-6-Trimethylsilanyl-Pyridine-3-Carbaldehyde
CAS No.	174092-75-2
Molecular Formula	C10H14INO2Si
Molecular Weight	335.22 g/mol
Synonyms	3-Formyl-4-iodo-2-methoxy-6-(trimethylsilyl)pyridine; 4-Iodo-2-methoxy-6-(trimethylsilyl)pyridine-3-carboxaldehyde; 6-(Trimethylsilyl)-4-iodo-2-methoxynicotinaldehyde; 4-Iodo-2-methoxy-6-trimethylsilylpyridine-3-carbaldehyde; 174092-75-2; 4-Iodo-2-methoxy-6-TMS-pyridine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 4-Iodo-2-Methoxy-6-Trimethylsilanyl-Pyridine-3-Carbaldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade specifications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool, and well-ventilated place. Due to its hygroscopic and easily oxidized nature, the container should be allowed to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.