Description

5-(Triethylsilyl)-4-Pentyn-1-Ol is a specialized organosilicon building block featuring both a terminal alkyne and a protected alcohol functional group. This bifunctional nature makes it a versatile intermediate for constructing complex molecular architectures in advanced synthetic chemistry. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science sectors for applications such as click chemistry, cross-coupling reactions, and the synthesis of novel polymers or liquid crystals.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of active pharmaceutical ingredients (APIs) via Sonogashira coupling or Huisgen cycloaddition (click chemistry).
• Agrochemical Synthesis: Used in constructing complex molecules for crop protection agents and herbicides.
• Materials Science: Building block for advanced polymers, dendrimers, and liquid crystalline materials requiring precise molecular geometry.
• Organic Synthesis: Versatile precursor for introducing silyl-protected alkyne moieties into larger, more complex organic molecules.
• Bioconjugation: Potential use in labeling biomolecules (proteins, peptides) due to the reactivity of the alkyne group.
• Chemical Research: Serves as a standard reagent in methodological development and catalysis studies in academic and industrial R&D labs.

Basic Information

Product Name	5-(Triethylsilyl)-4-Pentyn-1-Ol
CAS No.	174064-02-9
Molecular Formula	C11H22OSi
Molecular Weight	198.38 g/mol
Synonyms	4-Pentyn-1-ol, 5-(triethylsilyl)-; 5-(Triethylsilyl)pent-4-yn-1-ol; (4-Hydroxybut-1-yn-1-yl)triethylsilane; 5-Triethylsilyl-4-pentyn-1-ol; TES-protected 4-pentyn-1-ol; Triethyl(4-hydroxybut-1-yn-1-yl)silane
EINECS	Contact for details

Quality Control

Our 5-(Triethylsilyl)-4-Pentyn-1-Ol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, GC, and HPLC, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.