Description

5-Bromo-n-Methylpyridine-3-Sulfonamide is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, incorporating both a bromo substituent and a sulfonamide group, which makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its pyridine-sulfonamide scaffold for bioactivity.
• Material Science: Serves as a building block for creating functional polymers, liquid crystals, and organic electronic materials due to its aromatic and polar characteristics.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker in the design of enzyme inhibitors and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-fidelity brominated pyridine derivatives.

Basic Information

Product Name	5-Bromo-n-Methylpyridine-3-Sulfonamide
CAS No.	173999-19-4
Molecular Formula	C7H9BrN2O2S
Molecular Weight	265.13 g/mol
Synonyms	5-Bromo-N-methylpyridine-3-sulfonamide; 3-Pyridinesulfonamide, 5-bromo-N-methyl-; 5-Bromo-N-methyl-3-pyridinesulfonamide; 5-Bromo-3-(N-methylsulfamoyl)pyridine; 5-Bromo-N-methylnicotinsulfonamide
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-Methylpyridine-3-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that include data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.