Description

(2S)-Methyl 5-Chloro-2,3-Dihydro-2-Hydroxy-1-Oxo-1H-Indene-2-Carboxylate CAS NO 173903-18-9 is a high-purity chiral intermediate featuring a complex indene-based structure with multiple functional groups. This compound is critical for the synthesis of advanced pharmaceutical active ingredients and fine chemicals, where stereochemical purity is paramount. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the study of new catalytic systems.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals requiring specific stereochemistry.
• Academic & R&D: Utilized in university and corporate laboratories for methodological development and structure-activity relationship (SAR) studies.

Basic Information

Product Name	(2S)-Methyl 5-Chloro-2,3-Dihydro-2-Hydroxy-1-Oxo-1H-Indene-2-Carboxylate
CAS No.	173903-18-9
Molecular Formula	C12H11ClO4
Molecular Weight	254.67 g/mol
Synonyms	Methyl (2S)-5-chloro-2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate; (2S)-5-Chloro-2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylic acid methyl ester; (S)-Methyl 5-chloro-2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate; 5-Chloro-2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylic acid methyl ester, (2S)-; 173903-18-9; (2S)-5-Chloro-2-hydroxyindane-2-carboxylic acid methyl ester 1-one
EINECS	Contact for details

Quality Control

Our (2S)-Methyl 5-Chloro-2,3-Dihydro-2-Hydroxy-1-Oxo-1H-Indene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC to ensure enantiomeric excess (ee) and standard purity assays. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.