Description

(R)-1-(Pyrid-3-Yl)-2-Chloroethanol is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its defined stereochemistry and functional groups make it a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of drug candidates, particularly for central nervous system (CNS) agents and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides, where specific stereochemistry can impact biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic and R&D Laboratories: Employed in methodological studies for developing new synthetic routes and studying stereoselective reactions.
• Fine Chemical Production: A building block for creating complex, high-value molecules with applications in material science and electronics.

Basic Information

Product Name	(R)-1-(Pyrid-3-Yl)-2-Chloroethanol
CAS No.	173901-03-6
Molecular Formula	C7H8ClNO
Molecular Weight	157.60 g/mol
Synonyms	(R)-2-Chloro-1-(3-pyridinyl)ethanol; (R)-1-(3-Pyridyl)-2-chloroethanol; (R)-3-(2-Chloro-1-hydroxyethyl)pyridine; (R)-2-Chloro-1-(pyridin-3-yl)ethan-1-ol; (R)-β-Chloro-3-pyridineethanol; (R)-1-(3-Pyridinyl)-2-chloroethanol; (R)-1-(Pyridin-3-yl)-2-chloroethan-1-ol
EINECS	Contact for details

Quality Control

Our (R)-1-(Pyrid-3-Yl)-2-Chloroethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as chiral purity (enantiomeric excess), chemical purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.