Description

1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid, 4-Amino-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily sought after by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors for the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• API Development: Serves as a core scaffold or a protected intermediate in the multi-step synthesis of active pharmaceutical ingredients.
• Bioconjugation & Probe Synthesis: The amino and ester functional groups allow for further derivatization to create labeled compounds or molecular probes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid, 4-Amino-, 1,1-Dimethylethyl Ester
CAS No.	173898-20-9
Molecular Formula	C12H15N3O2
Molecular Weight	233.27 g/mol
Synonyms	4-Amino-1-(tert-butoxycarbonyl)-1H-pyrrolo[2,3-b]pyridine; 4-Amino-1-Boc-7-azaindole; tert-Butyl 4-amino-1H-pyrrolo[2,3-b]pyridine-1-carboxylate; 1-Boc-4-amino-7-azaindole; 4-Amino-1H-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester; 4-Amino-7-azaindole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-amino-7-azaindole
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid, 4-Amino-, 1,1-Dimethylethyl Ester adheres to stringent in-process controls and final release testing protocols. Each batch is analyzed using advanced chromatographic and spectroscopic techniques to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.