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(R)-Benzyl 1-(4-(1H-Pyrrolo[2,3-B]Pyridin-4-Ylcarbamoyl)Phenyl)Ethylcarbamate CAS NO 173897-93-3


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CAS No.:173897-93-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-Benzyl 1-(4-(1H-Pyrrolo[2,3-B]Pyridin-4-Ylcarbamoyl)Phenyl)Ethylcarbamate is a high-purity, chiral organic compound serving as a critical building block in advanced pharmaceutical research and development. Its value lies in its role as a sophisticated intermediate for synthesizing targeted therapeutic agents, particularly in oncology and kinase inhibitor programs. This product is essential for pharmaceutical companies, biotechnology firms, and advanced contract research organizations (CROs) engaged in the discovery and development of novel small-molecule drugs.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
  • Kinase Inhibitor Development: Used as a core structural component in the research and synthesis of potent and selective kinase inhibitors for cancer therapy.
  • Preclinical Research: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization campaigns.
  • Process Chemistry: Serves as a critical intermediate in scaling up synthetic routes from laboratory to pilot plant scale under GMP-like conditions.
  • Academic Research: Utilized in university and institutional labs for studying novel heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Item Details
Product Name (R)-Benzyl 1-(4-(1H-Pyrrolo[2,3-B]Pyridin-4-Ylcarbamoyl)Phenyl)Ethylcarbamate
CAS No. 173897-93-3
Molecular Formula C24H22N4O3
Molecular Weight 414.46 g/mol
Synonyms (R)-Benzyl (1-(4-((1H-pyrrolo[2,3-b]pyridin-4-yl)carbamoyl)phenyl)ethyl)carbamate; (R)-Benzyl N-[1-[4-[(1H-Pyrrolo[2,3-b]pyridin-4-yl)carbamoyl]phenyl]ethyl]carbamate; 173897-93-3; UNII-9Q9K4V4M5R; 9Q9K4V4M5R; SCHEMBL218496; BDBM50389379; AKOS025310999; A1-00819
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Quality Control

Our production of (R)-Benzyl 1-(4-(1H-Pyrrolo[2,3-B]Pyridin-4-Ylcarbamoyl)Phenyl)Ethylcarbamate adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and chiral integrity. Comprehensive Certificates of Analysis (COA) detailing all test results are provided to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 98.0% ee
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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