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(R)-Benzyl 1-(4-(1H-Pyrrolo[2,3-B]Pyridin-4-Ylcarbamoyl)Phenyl)Ethylcarbamate CAS NO 173897-93-3
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CAS No.:173897-93-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R)-Benzyl 1-(4-(1H-Pyrrolo[2,3-B]Pyridin-4-Ylcarbamoyl)Phenyl)Ethylcarbamate is a high-purity, chiral organic compound serving as a critical building block in advanced pharmaceutical research and development. Its value lies in its role as a sophisticated intermediate for synthesizing targeted therapeutic agents, particularly in oncology and kinase inhibitor programs. This product is essential for pharmaceutical companies, biotechnology firms, and advanced contract research organizations (CROs) engaged in the discovery and development of novel small-molecule drugs.
Application
- Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
- Kinase Inhibitor Development: Used as a core structural component in the research and synthesis of potent and selective kinase inhibitors for cancer therapy.
- Preclinical Research: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization campaigns.
- Process Chemistry: Serves as a critical intermediate in scaling up synthetic routes from laboratory to pilot plant scale under GMP-like conditions.
- Academic Research: Utilized in university and institutional labs for studying novel heterocyclic chemistry and developing new synthetic methodologies.
Basic Information
| Item | Details |
|---|---|
| Product Name | (R)-Benzyl 1-(4-(1H-Pyrrolo[2,3-B]Pyridin-4-Ylcarbamoyl)Phenyl)Ethylcarbamate |
| CAS No. | 173897-93-3 |
| Molecular Formula | C24H22N4O3 |
| Molecular Weight | 414.46 g/mol |
| Synonyms | (R)-Benzyl (1-(4-((1H-pyrrolo[2,3-b]pyridin-4-yl)carbamoyl)phenyl)ethyl)carbamate; (R)-Benzyl N-[1-[4-[(1H-Pyrrolo[2,3-b]pyridin-4-yl)carbamoyl]phenyl]ethyl]carbamate; 173897-93-3; UNII-9Q9K4V4M5R; 9Q9K4V4M5R; SCHEMBL218496; BDBM50389379; AKOS025310999; A1-00819 |
| EINECS | Contact for details |
Quality Control
Our production of (R)-Benzyl 1-(4-(1H-Pyrrolo[2,3-B]Pyridin-4-Ylcarbamoyl)Phenyl)Ethylcarbamate adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and chiral integrity. Comprehensive Certificates of Analysis (COA) detailing all test results are provided to support your regulatory and quality documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 97.0% |
| Chiral Purity (Chiral HPLC) | ≥ 98.0% ee |
| Water Content (KF) | ≤ 0.5% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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