Description

(5-Methyl-2-Oxo-1,3-Dioxol-4-Yl)Methyl 4-Nitrophenyl Carbonate is a specialized activated carbonate ester, widely recognized as a versatile reagent for introducing protecting groups and facilitating coupling reactions in synthetic organic chemistry. Its primary value lies in its high reactivity, particularly as a precursor for generating activated intermediates in the synthesis of complex molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for peptide synthesis, polymer chemistry, and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the protection of hydroxyl groups and the synthesis of carbonate-linked prodrugs and polymer conjugates.
• Peptide Chemistry: Used in solid-phase peptide synthesis (SPPS) as an activated carbonate for coupling amino acids or modifying peptide side chains.
• Polymer Functionalization: Serves as a monomer or cross-linking agent for creating functional polycarbonates and other specialty polymers with tailored properties.
• Bioconjugation: Facilitates the covalent attachment of drugs, dyes, or other molecules to proteins, antibodies, or nanoparticles for diagnostic and therapeutic applications.
• Agrochemical Research: Employed in the design and synthesis of novel herbicides, insecticides, and plant growth regulators that utilize carbonate functionalities.
• Material Science: Used in the surface modification of materials and the development of novel coatings and adhesives.

Basic Information

Item	Details
Product Name	(5-Methyl-2-Oxo-1,3-Dioxol-4-Yl)Methyl 4-Nitrophenyl Carbonate
CAS No.	173604-87-0
Molecular Formula	C12H9NO7
Molecular Weight	279.20 g/mol
Synonyms	4-Nitrophenyl (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl carbonate; 4-Nitrophenyl carbonic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester; 4-NPMC; NPMC; 4-Nitrophenyl methylene carbonate acetonide; Acetone ketal of (hydroxymethyl) 4-nitrophenyl carbonate
EINECS	Contact for details

Quality Control

Our production of (5-Methyl-2-Oxo-1,3-Dioxol-4-Yl)Methyl 4-Nitrophenyl Carbonate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and process development. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.