Description

3-(4-Fluoro-Phenyl)-Piperidin-3-Ol Hydrochloride is a high-purity pharmaceutical intermediate and research chemical of significant synthetic interest. Its core value lies in its role as a versatile building block for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and psychiatric drug discovery. This compound is essential for research chemists, process development scientists, and manufacturers in the pharmaceutical and biotechnology industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting neurological and psychiatric disorders.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Research & Development (R&D): Critical for academic and industrial research focused on piperidine-based pharmacophores and fluorinated compounds.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing processes.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API production.

Basic Information

Product Name	3-(4-Fluoro-Phenyl)-Piperidin-3-Ol Hydrochloride
CAS No.	173447-91-1
Molecular Formula	C11H14FNO·HCl
Molecular Weight	231.70 g/mol
Synonyms	3-(4-Fluorophenyl)-3-piperidinol hydrochloride; 3-(p-Fluorophenyl)-3-hydroxypiperidine hydrochloride; 3-Piperidinol, 3-(4-fluorophenyl)-, hydrochloride; 4-Fluoro-α-(3-hydroxy-3-piperidyl)benzyl alcohol hydrochloride; 3-(4-Fluorophenyl)piperidin-3-ol HCl
EINECS	Contact for details

Quality Control

Our 3-(4-Fluoro-Phenyl)-Piperidin-3-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.