Description

T-Butyl 3-Iodobenzoate is a high-purity, versatile chemical intermediate featuring a halogenated aromatic ring system protected by a tert-butyl ester group. This compound is valued for its role in facilitating complex organic syntheses, particularly in the construction of pharmaceutical and advanced material scaffolds. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in cross-coupling reactions and as a building block for active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a halogenated benzoate moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor in the development of liquid crystals, organic semiconductors, and advanced polymers.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings to form new carbon-carbon bonds.
• Organic Synthesis Research: Employed in academic and industrial R&D labs for method development and the construction of complex organic molecules.
• Chemical Derivatization: The tert-butyl ester group can be selectively cleaved under mild acidic conditions, allowing for further functionalization of the benzoic acid core.

Basic Information

Product Name	T-Butyl 3-Iodobenzoate
CAS No.	173406-17-2
Molecular Formula	C11H13IO2
Molecular Weight	304.13 g/mol
Synonyms	3-Iodobenzoic Acid tert-Butyl Ester; tert-Butyl 3-Iodobenzoate; Benzoic acid, 3-iodo-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 3-iodobenzoate; 3-Iodo-benzoic acid tert-butyl ester; T-Butyl m-Iodobenzoate; m-Iodobenzoic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our T-Butyl 3-Iodobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.