Description

1H-Xanthine, 3,7-Dimethyl-1-(3-Trimethylsilylpropyl)- is a high-purity, organosilicon-modified xanthine derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in the unique combination of the xanthine pharmacophore with a silyl-protecting group, enabling precise synthetic pathways for novel bioactive molecules. This compound is essential for medicinal chemists and R&D teams in the pharmaceutical and biotechnology sectors focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel adenosine receptor antagonists and phosphodiesterase (PDE) inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new drug candidates targeting neurological and cardiovascular diseases.
• Chemical Biology Probes: Serves as a precursor for labeled compounds used in biochemical assays and target identification.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental studies on purine chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	1H-Xanthine, 3,7-Dimethyl-1-(3-Trimethylsilylpropyl)-
CAS No.	173347-43-8
Molecular Formula	C13H22N4O2Si
Molecular Weight	294.43 g/mol
Synonyms	3,7-Dimethyl-1-(3-trimethylsilylpropyl)-1H-purine-2,6-dione; 1-(3-Trimethylsilylpropyl)-3,7-dimethylxanthine; 3,7-Dimethyl-1-(3-trimethylsilylpropyl)xanthine; TMS-propyl-theobromine analog; 1H-Purine-2,6-dione, 3,7-dimethyl-1-[3-(trimethylsilyl)propyl]-; Silylated xanthine derivative; CAS 173347-43-8
EINECS	Contact for details

Quality Control

Our 1H-Xanthine, 3,7-Dimethyl-1-(3-Trimethylsilylpropyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.