Description

6-((Trimethylsilyl)Ethynyl)Pyridin-2-Amine CAS NO 173314-97-1 is a specialized pyridine derivative featuring a trimethylsilyl-protected ethynyl group, serving as a versatile and valuable building block in advanced organic synthesis. This compound is particularly significant for its role in cross-coupling reactions and as a precursor for complex heterocyclic systems. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its functional groups for creating targeted bioactive molecules.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, conductive materials, and metal-organic frameworks (MOFs).
• Ligand Synthesis: Utilized in organometallic chemistry to create sophisticated ligands for catalysis and coordination chemistry applications.
• Chemical Research & Development: A critical reagent in academic and industrial R&D for exploring new synthetic pathways and constructing complex molecular architectures.
• Fluorescent Probe Development: The pyridine-amine core and alkyne functionality make it suitable for synthesizing fluorescent tags and sensors for biological imaging.

Basic Information

Product Name	6-((Trimethylsilyl)Ethynyl)Pyridin-2-Amine
CAS No.	173314-97-1
Molecular Formula	C10H16N2Si
Molecular Weight	192.34 g/mol
Synonyms	2-Amino-6-((trimethylsilyl)ethynyl)pyridine; 6-(Trimethylsilylethynyl)pyridin-2-amine; 6-(2-Trimethylsilylethynyl)-2-pyridinamine; 2-Pyridinamine, 6-[(trimethylsilyl)ethynyl]-; TMS-Ethynyl-2-aminopyridine; 6-(Trimethylsilylethynyl)-2-aminopyridine; 6-(TMS-ethynyl)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our production of 6-((Trimethylsilyl)Ethynyl)Pyridin-2-Amine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.