Description

Methyl 6-Iodonicotinate is a high-purity, versatile iodinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce iodine functionality for further cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings to form biaryl and other complex structures.
• Chemical Research: Employed in academic and industrial R&D for methodology development and exploring new synthetic pathways.
• Ligand Preparation: Useful for synthesizing functionalized pyridine-based ligands for catalysis and coordination chemistry.

Basic Information

Product Name	Methyl 6-Iodonicotinate
CAS No.	173157-33-0
Molecular Formula	C7H6INO2
Molecular Weight	263.03 g/mol
Synonyms	6-Iodonicotinic Acid Methyl Ester; Methyl 6-Iodopyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 6-iodo-, methyl ester; 6-Iodo-3-pyridinecarboxylic acid methyl ester; Methyl 6-iodonicotinate; 6-Iodonicotinic acid methyl ester; 3-Carbomethoxy-6-iodopyridine
EINECS	Contact for details

Quality Control

Our Methyl 6-Iodonicotinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, from research to scale-up development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.