Description

1-Azabicyclo[3.1.0]Hexane-2-Carboxylicacid,Ethylester,(2S-Cis)-(9Ci) CAS NO 172879-75-3 is a high-purity, stereochemically defined bicyclic proline derivative, serving as a critical chiral building block in advanced organic synthesis. Its rigid, fused ring structure and defined stereochemistry make it invaluable for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs), particularly in the areas of protease inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for targeting specific enzymatic pathways.
• Protease Inhibitor Synthesis: Core building block for constructing sophisticated molecules designed to inhibit proteases, a major class of drug targets.
• Peptidomimetics Development: Used to create non-peptide compounds that mimic the structure and function of peptides, enhancing metabolic stability and bioavailability.
• Asymmetric Synthesis: Employed as a chiral auxiliary or scaffold to induce stereoselectivity in complex chemical transformations.
• Medicinal Chemistry Research: Facilitates structure-activity relationship (SAR) studies by providing a constrained, three-dimensional framework.
• Fine Chemical Production: Serves as a specialized intermediate in the multi-step synthesis of high-value, complex organic molecules for various industrial applications.

Basic Information

Item	Details
Product Name	1-Azabicyclo[3.1.0]Hexane-2-Carboxylicacid,Ethylester,(2S-Cis)-(9Ci)
CAS No.	172879-75-3
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	(2S,5S)-Ethyl 1-azabicyclo[3.1.0]hexane-2-carboxylate; (2S,5S)-1-Azabicyclo[3.1.0]hexane-2-carboxylic acid ethyl ester; Ethyl (1S,5S)-1-azabicyclo[3.1.0]hexane-2-carboxylate; cis-Ethyl 1-azabicyclo[3.1.0]hexane-2-carboxylate; Bicycloproline ethyl ester; (2S-cis)-Ethyl 1-azabicyclo[3.1.0]hexane-2-carboxylate; 172879-75-3
EINECS	Contact for details

Quality Control

Every batch of our 1-Azabicyclo[3.1.0]Hexane-2-Carboxylicacid,Ethylester,(2S-Cis)-(9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC, to guarantee high enantiomeric purity and chemical identity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.