Description

3-Bromo-N,n-Bis(Trimethylsilyl)Propan-1-Amine is a specialized organosilicon compound featuring a bromoalkylamine core protected by trimethylsilyl groups. This unique structure makes it a valuable silylating agent and protected synthetic intermediate in advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules and modifying surface functionalities.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring protected amine functionalities or serving as precursors to nitrogen-containing heterocycles.
• Agrochemical Synthesis: Serves as a key building block for creating novel pesticides, herbicides, and plant growth regulators that incorporate bromine and silicon moieties.
• Silylating Agent: Employed to introduce the bulky trimethylsilyl (TMS) protecting group onto amines, alcohols, or other nucleophiles, altering reactivity and solubility profiles during multi-step syntheses.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty silicon-based polymers, resins, and surface coatings.
• Organic Synthesis Reagent: Facilitates carbon-nitrogen bond formation reactions and is used in nucleophilic substitution reactions where the bromine serves as a good leaving group.
• Chemical Research: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Item	Detail
Product Name	3-Bromo-N,n-Bis(Trimethylsilyl)Propan-1-Amine
CAS No.	172851-95-5
Molecular Formula	C9H24BrNSi2
Molecular Weight	282.37 g/mol
Synonyms	1-Amino-3-bromopropane, N,N-Bis(trimethylsilyl) derivative; 3-Bromopropylamine, N,N-Bis(trimethylsilyl)-; N,N-Bis(trimethylsilyl)-3-bromopropylamine; 3-Bromo-N,N-bis(trimethylsilyl)propylamine; (3-Bromopropyl)bis(trimethylsilyl)amine; TMS-protected 3-bromopropylamine; N-(3-Bromopropyl)-1,1,1-trimethyl-N-(trimethylsilyl)silanamine
EINECS	Contact for details

Quality Control

Our 3-Bromo-N,n-Bis(Trimethylsilyl)Propan-1-Amine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality systems are designed to meet the stringent requirements of research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.