Description

Cyclopentanecarboxylic Acid, 2-Hydroxy-1-Methyl-, Methyl Ester, (1S-Trans)- is a high-purity chiral intermediate of significant value in advanced organic synthesis. This compound matters for its role as a key building block in the production of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty fragrances.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific stereochemical requirements.
• Fine Chemical Production: Serves as a versatile building block for creating complex molecules in specialty chemistry applications.
• Fragrance & Flavor Industry: Potential use in the synthesis of high-value chiral aroma chemicals and flavor compounds.
• Academic & Industrial Research: A valuable reagent for methodological development in asymmetric synthesis and catalysis studies.
• Material Science: Can be utilized in the development of specialized polymers and liquid crystals requiring chiral monomers.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Hydroxy-1-Methyl-, Methyl Ester, (1S-Trans)-
CAS No.	172825-20-6
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(1S,2R)-2-Hydroxy-1-methylcyclopentanecarboxylic acid methyl ester; Methyl (1S,2R)-2-hydroxy-1-methylcyclopentanecarboxylate; (1S-trans)-2-Hydroxy-1-methylcyclopentanecarboxylic acid methyl ester; trans-2-Hydroxy-1-methylcyclopentanecarboxylic acid methyl ester; (1S,2R)-Methyl 2-hydroxy-1-methylcyclopentanecarboxylate; Chiral cyclopentane ester; 2-Hydroxy-1-methylcyclopentanecarboxylic acid methyl ester (trans-)
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 2-Hydroxy-1-Methyl-, Methyl Ester, (1S-Trans)- is manufactured under strict quality systems to ensure batch-to-batch consistency and high chiral purity. We provide comprehensive analytical data, including chiral HPLC or GC analysis, to verify identity, purity, and enantiomeric excess (ee). Certificates of Analysis (COA) detailing all specifications are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.