Description

n-[1,4,5,6,7,8-Hexahydro-6,7-Dimethyl-4-Oxo-5-(3-Pyridinylcarbonyl)-2-Pteridinyl]-2-Methyl-Propanamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel therapeutic agents, particularly in oncology and targeted drug development. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially kinase inhibitors.
• Oncology Research: Used in the discovery and development of targeted cancer therapies due to its specific molecular scaffold.
• Biochemical Research: Serves as a reference standard or a tool compound for studying enzyme inhibition and cellular signaling pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and structure-activity relationship (SAR) studies.

Basic Information

Product Name	n-[1,4,5,6,7,8-Hexahydro-6,7-Dimethyl-4-Oxo-5-(3-Pyridinylcarbonyl)-2-Pteridinyl]-2-Methyl-Propanamide
CAS No.	172758-08-6
Molecular Formula	C20H22N6O3
Molecular Weight	394.43 g/mol
Synonyms	2-Methyl-N-[6,7-dimethyl-4-oxo-5-(pyridine-3-carbonyl)-1,4,5,6,7,8-hexahydropteridin-2-yl]propanamide; 2-Methylpropanamide, N-[1,4,5,6,7,8-hexahydro-6,7-dimethyl-4-oxo-5-(3-pyridinylcarbonyl)-2-pteridinyl]-; Pteridine-2-propanamide derivative; CAS 172758-08-6; Advanced pteridine intermediate; Kinase inhibitor intermediate
EINECS	Contact for details

Quality Control

Our n-[1,4,5,6,7,8-Hexahydro-6,7-Dimethyl-4-Oxo-5-(3-Pyridinylcarbonyl)-2-Pteridinyl]-2-Methyl-Propanamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, it is recommended to handle it under a dry atmosphere and keep the container tightly sealed after each use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.