Description

Diethyl 2-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]Malonate is a high-purity, versatile chemical intermediate essential for advanced organic synthesis. This compound is valued for its unique pyridine-based structure, which serves as a critical building block in the development of complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the trifluoromethyl and chloro substituents for enhanced bioactivity.
• Material Science Research: Serves as a building block for creating functionalized ligands, polymers, and advanced organic materials with specific electronic properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and the creation of novel heterocyclic compounds.
• Custom Synthesis: A vital starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	Diethyl 2-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]Malonate
CAS No.	172527-71-8
Molecular Formula	C13H13ClF3NO4
Molecular Weight	339.69 g/mol
Synonyms	Diethyl (3-Chloro-5-(trifluoromethyl)pyridin-2-yl)malonate; 2-Pyridinecarboxylic acid, 3-chloro-5-(trifluoromethyl)-, 2-(diethyl malonate); Diethyl (3-chloro-5-trifluoromethyl-2-pyridyl)malonate; 172527-71-8; 3-Chloro-5-(trifluoromethyl)pyridine-2-ylmalonic acid diethyl ester; Malonic acid, (3-chloro-5-(trifluoromethyl)-2-pyridinyl)-, diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl 2-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]Malonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.