Description

3-Pyridinecarboxylic Acid,5-Ethyl-1,2-Dihydro-4-Hydroxy-6-Methyl-2-Oxo-, Ethyl Ester is a high-purity, synthetically derived pyridine derivative serving as a critical advanced pharmaceutical intermediate (API intermediate). This compound matters for its role in the synthesis of complex active ingredients, where its specific molecular framework is essential for constructing target pharmacophores. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Organic Synthesis Reagent: Used in research-scale and pilot-scale organic reactions to introduce its unique substituted pyridine moiety into more complex molecules.
• Agrochemical Research: Serves as a precursor in the development of new-generation pesticides and herbicides, leveraging its heterocyclic structure.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with specific electronic or binding properties.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) settings for methodological studies and discovery chemistry.

Basic Information

Item	Detail
Product Name	3-Pyridinecarboxylic Acid,5-Ethyl-1,2-Dihydro-4-Hydroxy-6-Methyl-2-Oxo-, Ethyl Ester
CAS No.	172470-04-1
Molecular Formula	C12H15NO4
Molecular Weight	237.25 g/mol
Synonyms	5-Ethyl-1,2-dihydro-4-hydroxy-6-methyl-2-oxo-3-pyridinecarboxylic acid ethyl ester; Ethyl 5-ethyl-1,2-dihydro-4-hydroxy-6-methyl-2-oxonicotinate; 5-Ethyl-4-hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid ethyl ester; ABT-089 intermediate; GTS-21 intermediate; DMXB-A intermediate; TC-1698 intermediate; Ispronicline intermediate
EINECS	Contact for details

Quality Control

Our production of this pharmaceutical-grade intermediate adheres to stringent quality protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. We ensure compliance with ICH guidelines for impurities. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.