Description

4-Azidobutanol 1-Acetate is a specialized bifunctional organic compound that serves as a valuable building block in advanced chemical synthesis. Its molecular structure, featuring both an azide group and an acetate-protected alcohol, makes it a critical reagent for click chemistry applications, particularly in bioconjugation and polymer science. This compound is essential for researchers and manufacturers in the pharmaceutical, biotech, and materials science industries who require reliable, high-purity intermediates for developing novel therapeutics, diagnostics, and functional polymers.

Application

• Bioconjugation Linker: A key reagent in copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry for labeling proteins, antibodies, and oligonucleotides.
• Polymer Functionalization: Used to introduce azide handles into polymer backbones (e.g., PEGs, polyesters) for subsequent cross-linking or attachment of bioactive molecules.
• Pharmaceutical Intermediate: Serves as a versatile synthon in the synthesis of prodrugs and targeted drug delivery systems.
• Materials Science: Employed in the surface modification of nanoparticles and biomaterials to create bioactive interfaces.
• Chemical Probe Synthesis: Facilitates the development of activity-based probes and diagnostic agents for biochemical research.
• Peptide Modification: Enables site-specific modification of peptides during solid-phase peptide synthesis (SPPS).

Basic Information

Product Name	4-Azidobutanol 1-Acetate
CAS No.	172468-38-1
Molecular Formula	C6H11N3O2
Molecular Weight	157.17 g/mol
Synonyms	4-Azidobutyl acetate; 1-Acetoxy-4-azidobutane; 4-Azido-1-butanol acetate; Butanol, 4-azido-, 1-acetate; 4-Azidobutanol acetate; N3(CH2)4OCOCH3; Azido-PEG4-acetate (related); 4-Azidobutyl ethanoate
EINECS	Contact for details

Quality Control

Our 4-Azidobutanol 1-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for research and production. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated). This compound is moisture-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.