Description

Motolimod is a potent and selective agonist for Toll-like receptor 7 (TLR7), functioning as a key immunostimulant. This compound is of significant interest for its ability to activate innate and adaptive immune responses, making it a valuable tool in immunological research and therapeutic development. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology, antiviral therapies, and vaccine adjuvants.

Application

• Immuno-oncology Research: Investigated as a potential therapeutic agent to stimulate anti-tumor immune responses in various cancer models.
• Vaccine Adjuvant Development: Used in preclinical studies to enhance the efficacy of vaccines by potently activating antigen-presenting cells.
• Antiviral Drug Research: Explored for its role in boosting immune defense mechanisms against viral infections.
• TLR7 Pathway Studies: Serves as a critical pharmacological tool for elucidating TLR7 signaling and function in immune cells.
• Autoimmune Disease Models: Applied in research to understand the role of TLR activation in autoimmune and inflammatory conditions.
• Combination Therapy Protocols: Evaluated in conjunction with other immunomodulators or checkpoint inhibitors to achieve synergistic effects.

Basic Information

Product Name	Motolimod
CAS No.	172377-52-5
Molecular Formula	C17H21N7O2
Molecular Weight	355.40 g/mol
Synonyms	VTX-2337; VTX2337; 1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol; 1-[4-Amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methyl-2-propanol; Motolimodum; UNII-8JQ5607EO5; 8JQ5607EO5
EINECS	Contact for details

Quality Control

Our Motolimod CAS NO 172377-52-5 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.