Description

(2S)-3,6-Dihydro-2H-Pyran-2-Ylmethanol CAS NO 172323-66-9 is a high-purity chiral building block featuring a protected dihydropyran alcohol moiety. This compound is valued for its role as a versatile synthetic intermediate in the production of complex, stereochemically defined molecules. It is primarily sought after by research and development chemists and process scale-up teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring specific stereochemistry.
• Asymmetric Synthesis: Used in the construction of complex natural products and bioactive molecules where the (2S) configuration is critical for activity.
• Medicinal Chemistry Research: Employed in drug discovery programs for the preparation of novel compound libraries targeting various disease pathways.
• Fine Chemical Production: Serves as a building block for specialty chemicals, agrochemicals, and advanced materials requiring high enantiomeric purity.
• Ligand and Catalyst Development: Can be utilized in the synthesis of chiral ligands or organocatalysts for enantioselective transformations.

Basic Information

Product Name	(2S)-3,6-Dihydro-2H-Pyran-2-Ylmethanol
CAS No.	172323-66-9
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	(2S)-3,6-Dihydro-2H-pyran-2-methanol; (S)-3,6-Dihydro-2H-pyran-2-ylmethanol; (S)-(-)-3,6-Dihydro-2H-pyran-2-ylmethanol; (2S)-3,6-Dihydro-2H-pyran-2-ylcarbinol; (S)-DHP-methanol; (2S)-Dihydropyran-2-ylmethanol; (S)-Tetrahydro-2H-pyran-2-ylmethanol (unsaturated form)
EINECS	Contact for details

Quality Control

Our (2S)-3,6-Dihydro-2H-Pyran-2-Ylmethanol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.