Description

tert-Butyl 12-Bromododecanoate is a high-purity organic intermediate featuring a bromoalkyl chain protected by a tert-butyl ester group. This compound is valued for its role as a versatile building block in advanced organic synthesis, enabling the controlled introduction of long-chain functionalities. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring long alkyl chain modifications or prodrug strategies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate specific hydrophobic side chains.
• Polymer & Material Science: Serves as a functional monomer or chain transfer agent in the production of specialty polymers, surfactants, and liquid crystals.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Lipid & Peptide Conjugation: Employed in bioconjugation chemistry to attach lipid moieties or other hydrophobic tags to peptides, proteins, or drug delivery systems.
• Organic Synthesis Reagent: Utilized in nucleophilic substitution and esterification/transesterification reactions to introduce protected carboxylic acid functionalities.

Basic Information

Product Name	tert-Butyl 12-Bromododecanoate
CAS No.	172304-05-1
Molecular Formula	C₁₆H₃₁BrO₂
Molecular Weight	335.32 g/mol
Synonyms	12-Bromododecanoic Acid tert-Butyl Ester; tert-Butyl 12-Bromolaurate; Dodecanoic Acid, 12-Bromo-, 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl 12-Bromododecanoate; 12-Bromo-1-tert-butoxydodecan-1-one; t-Butyl 12-bromododecanoate; Bromododecanoic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 12-Bromododecanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.