Description

1,2,7,8-Indolizinetetrol, Octahydro-, Tetraacetate (Ester), 1S-(1.Alpha.,2.Beta.,7.Alpha.,8.Alpha.,8A.Alpha.)- is a high-purity, stereochemically defined indolizine derivative, serving as a critical advanced intermediate in complex organic synthesis. Its value lies in providing a functionalized, protected polyol scaffold that enables the efficient construction of biologically active molecules and natural product analogs. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where precise stereochemistry and functional group manipulation are paramount for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex alkaloids, glycosidase inhibitors, and other bioactive nitrogen-containing heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides that require specific chiral centers for optimal activity.
• Organic Synthesis Reagent: Serves as a versatile chiral template in asymmetric synthesis and medicinal chemistry programs.
• Academic & Institutional Research: A valuable tool for studying synthetic methodology, reaction mechanisms, and structure-activity relationships (SAR).
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals and flavors/fragrances precursors.

Basic Information

Item	Detail
Product Name	1,2,7,8-Indolizinetetrol, Octahydro-, Tetraacetate (Ester), 1S-(1.Alpha.,2.Beta.,7.Alpha.,8.Alpha.,8A.Alpha.)-
CAS No.	171925-21-6
Molecular Formula	C18H26O8
Molecular Weight	370.40 g/mol
Synonyms	(1S,2R,7S,8S,8aS)-Octahydro-1,2,7,8-indolizinetetrol Tetraacetate; (1S,2R,7S,8S,8aS)-1,2,7,8-Tetrakis(acetyloxy)octahydroindolizine; 1S-(1α,2β,7α,8α,8aα)-Octahydro-1,2,7,8-indolizinetetrol Tetraacetate; Indolizine-1,2,7,8-tetrol, octahydro-, tetraacetate, (1S,2R,7S,8S,8aS)-; CAS 171925-21-6; Protected Indolizine Polyol Ester; Chiral Indolizine Tetraacetate.
EINECS	Contact for details

Quality Control

Our production of 1,2,7,8-Indolizinetetrol, Octahydro-, Tetraacetate (Ester) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC and structural confirmation by NMR and IR spectroscopy, to ensure high chemical and stereochemical purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage under optimal conditions, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.