Description

Ethyl 6-Chloro-5-Nitro-3-Pyridinecarboxylate is a high-purity, versatile pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering both an ester group and a nitro-chloro substituted aromatic ring for sequential functionalization. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to construct complex heterocyclic scaffolds for active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides, leveraging the pyridine core's bioactivity.
• Material Science Research: Used in the development of specialty chemicals, ligands for catalysis, and functionalized polymers.
• Chemical Biology: Serves as a probe or linker molecule in bioconjugation and the development of biochemical tools.
• Academic & R&D: Fundamental reagent for methodological studies in organic chemistry, including cross-coupling and nucleophilic substitution reactions.

Basic Information

Product Name	Ethyl 6-Chloro-5-Nitro-3-Pyridinecarboxylate
CAS No.	171876-22-5
Molecular Formula	C8H7ClN2O4
Molecular Weight	230.60 g/mol
Synonyms	Ethyl 6-chloro-5-nitronicotinate; 3-Pyridinecarboxylic acid, 6-chloro-5-nitro-, ethyl ester; 6-Chloro-5-nitro-3-pyridinecarboxylic acid ethyl ester; Ethyl 6-chloro-5-nitropyridine-3-carboxylate; 5-Nitro-6-chloronicotinic acid ethyl ester; 6-Chloro-5-nitronicotinic acid ethyl ester; Ethyl 5-nitro-6-chloronicotinate
EINECS	Contact for details

Quality Control

Our Ethyl 6-Chloro-5-Nitro-3-Pyridinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.