Description

1,3,5-Tri-o-Benzoyl-α-L-Ribofuranose is a key benzoylated ribose derivative, serving as a crucial chiral intermediate in advanced organic synthesis. Its primary value lies in providing a protected ribofuranose scaffold, enabling the precise construction of nucleoside analogs and other complex bioactive molecules. This high-purity building block is essential for research and development in the pharmaceutical industry, particularly for antiviral and anticancer drug discovery programs.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside and nucleotide analogs.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Anticancer Agent Synthesis: Serves as a precursor in the creation of chemotherapeutic compounds that interfere with DNA/RNA synthesis.
• Carbohydrate Chemistry: A protected sugar derivative for glycosylation reactions and the synthesis of complex oligosaccharides.
• Process Chemistry & Scale-up: Employed in route development and cGMP manufacturing for clinical trial material.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleic acid metabolism.

Basic Information

Product Name	1,3,5-Tri-o-Benzoyl-α-L-Ribofuranose
CAS No.	171866-30-1
Molecular Formula	C26H22O8
Molecular Weight	462.45 g/mol
Synonyms	1,3,5-Tri-O-benzoyl-α-L-ribofuranose; α-L-Ribofuranose 1,3,5-tribenzoate; 2-Deoxy-1,3,5-tri-O-benzoyl-α-L-erythro-pentofuranose; Tribenzoyl-α-L-ribofuranose; L-Ribofuranose tribenzoate; 1,3,5-Tri-O-benzoyl-2-deoxy-α-L-ribofuranose; NSC 339524
EINECS	Contact for details

Quality Control

Our 1,3,5-Tri-o-Benzoyl-α-L-Ribofuranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.