Description

tert-Butyl 3-Bromobenzylcarbamate is a high-purity organic building block and pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and advanced material science. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bromine atom for further functionalization.
• Peptidomimetics & PROTACs: Serves as a protected amine precursor in the construction of peptide analogs and Proteolysis Targeting Chimeras (PROTACs) for drug discovery.
• Material Science Research: Employed as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	tert-Butyl 3-Bromobenzylcarbamate
CAS No.	171663-13-1
Molecular Formula	C12H16BrNO2
Molecular Weight	286.17 g/mol
Synonyms	Carbamic acid, N-[(3-bromophenyl)methyl]-, 1,1-dimethylethyl ester; tert-Butyl N-[(3-bromophenyl)methyl]carbamate; 3-Bromobenzylcarbamic acid tert-butyl ester; Boc-3-bromobenzylamine; N-Boc-3-bromobenzylamine; N-(tert-Butoxycarbonyl)-3-bromobenzylamine; 1-Boc-3-bromobenzylamine; (3-Bromobenzyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Bromobenzylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP and ISO standards for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.