Description

Ethyl 1-Oxaspiro[2.5]octane-6-carboxylate is a high-value, specialized spirocyclic building block used in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and complex agrochemicals due to its unique constrained bicyclic structure. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides with novel modes of action.
• Material Science: Serves as a precursor for specialty polymers and advanced materials requiring specific stereochemistry and rigidity.
• Asymmetric Synthesis: Employed as a scaffold or chiral auxiliary in catalytic asymmetric reactions to induce high enantioselectivity.
• Fragrance & Flavor Chemistry: Potential intermediate for creating unique, stable odorant molecules with complex spirocyclic notes.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploration of new chemical space.

Basic Information

Product Name	Ethyl 1-Oxaspiro[2.5]octane-6-carboxylate
CAS No.	171361-65-2
Molecular Formula	C10H16O3
Molecular Weight	184.23 g/mol
Synonyms	Ethyl 1-oxaspiro[2.5]octane-6-carboxylate; 6-Carbethoxy-1-oxaspiro[2.5]octane; Ethyl 6-oxaspiro[2.5]octane-1-carboxylate; 1-Oxaspiro[2.5]octane-6-carboxylic acid, ethyl ester; Spirocyclic oxirane ester; Ethyl oxaspirooctanecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 1-Oxaspiro[2.5]octane-6-carboxylate is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR/IR for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under an inert atmosphere (nitrogen or argon), please contact our technical team.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.