Description

L-Proline, 3-Ethyl-, Methyl Ester, cis- (9Ci) is a high-purity, non-proteinogenic proline derivative characterized by its specific stereochemistry and functionalized side chain. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in protease inhibitor and peptide-based therapeutic research.
• Peptidomimetics Development: Used to introduce conformational constraints and novel side-chain functionalities into peptide analogs to enhance stability and biological activity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective reactions to construct enantiomerically pure compounds.
• Chemical Biology Research: Utilized in the study of enzyme-substrate interactions and the design of molecular probes.
• Agrochemical Synthesis: Acts as an intermediate in the development of advanced, biologically active compounds for crop protection.
• Academic & Industrial R&D: Serves as a valuable reagent for methodological development in organic chemistry and material science laboratories.

Basic Information

Product Name	L-Proline, 3-Ethyl-, Methyl Ester, cis- (9Ci)
CAS No.	171232-79-4
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	cis-3-Ethyl-L-proline methyl ester; Methyl cis-3-ethyl-L-prolinate; (2S,3S)-3-Ethylpyrrolidine-2-carboxylic acid methyl ester; L-Proline, 3-ethyl-, methyl ester, cis-; (2S,3S)-3-Ethyl-2-pyrrolidinecarboxylic acid methyl ester; Methyl (2S,3S)-3-ethylpyrrolidine-2-carboxylate; cis-3-Ethyl-L-proline methyl ester (9CI)
EINECS	Contact for details

Quality Control

Our L-Proline, 3-Ethyl-, Methyl Ester, cis- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques, including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Optical Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.