Description

L-Proline, 3-Ethyl-, Methyl Ester, trans- (9Ci) is a high-purity, non-natural proline derivative characterized by its specific stereochemistry and functional groups. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals where precise stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for protease inhibitors and other biologically active molecules.
• Peptidomimetics Research: Used to synthesize modified peptide structures to enhance stability, bioavailability, or receptor binding affinity.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to induce chirality in target molecules.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme mechanisms or protein-protein interactions.
• Agrochemical Research: Potential intermediate in the synthesis of advanced, chiral active ingredients for crop protection.
• Academic & Process Chemistry: Utilized in methodological studies and scale-up process development for complex organic molecules.

Basic Information

Product Name	L-Proline, 3-Ethyl-, Methyl Ester, trans- (9Ci)
CAS No.	171232-78-3
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	trans-3-Ethyl-L-proline methyl ester; Methyl (2S,3S)-3-ethylpyrrolidine-2-carboxylate; (2S,3S)-3-Ethylpyrrolidine-2-carboxylic acid methyl ester; L-Proline, 3-ethyl-, methyl ester, trans-; (2S,3S)-2-(Methoxycarbonyl)-3-ethylpyrrolidine; trans-3-Ethyl-L-proline methyl ester hydrochloride (salt form); (2S,3S)-3-Ethyl-1,2-pyrrolidinedicarboxylic acid 2-methyl ester
EINECS	Contact for details

Quality Control

Our L-Proline, 3-Ethyl-, Methyl Ester, trans- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical research and fine chemical synthesis. A detailed Certificate of Analysis (COA) providing full specification results is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is compatible with strong alkali/organic solvents; ensure storage areas are appropriate for such materials. Keep away from incompatible substances.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.