Description

2-Fluoro-5-Iodopyridine is a versatile halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a highly valuable intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Used to create specialized ligands for transition metal catalysis, enabling more efficient cross-coupling reactions like Suzuki-Miyaura and Buchwald-Hartwig amination.
• Material Science Research: Intermediate in the development of organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology Probes: Serves as a starting point for synthesizing molecular probes and tags used in bioimaging and diagnostic assays.
• Custom Synthesis and R&D: Employed in contract research and fine chemical production for bespoke molecule construction.

Basic Information

Product Name	2-Fluoro-5-Iodopyridine
CAS No.	171197-80-1
Molecular Formula	C5H3FIN
Molecular Weight	222.99 g/mol
Synonyms	5-Iodo-2-fluoropyridine; 2-Fluoro-5-iodopyridine; 5-Iodo-2-fluoro-pyridine; Pyridine, 2-fluoro-5-iodo-; 2-Fluoropyridin-5-yl iodide; 2-Fluoro-5-iodo-pyridine; 2-Fluoro-5-iodopyridine (9CI)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored away from direct light and moisture sources. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.