Description

4-Bocamino-Nicotinic Acid is a high-purity, protected nicotinic acid derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Peptide Mimetics & Conjugation: Used to introduce the nicotinic acid pharmacophore into peptide backbones or for bioconjugation strategies.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, insecticides, and plant growth regulators.
• Ligand & Catalyst Development: Employed in the creation of novel ligands for metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Material Science: A monomer or functionalization agent for advanced polymers and functional materials.

Basic Information

Product Name	4-Bocamino-Nicotinic Acid
CAS No.	171178-34-0
Molecular Formula	C11H14N2O4
Molecular Weight	238.24 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]nicotinic Acid; 4-(Boc-amino)nicotinic Acid; 4-(tert-Butoxycarbonylamino)pyridine-3-carboxylic Acid; 3-Pyridinecarboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-; 4-Boc-aminonicotinic Acid; 4-N-Boc-aminonicotinic Acid; Boc-4-Aminonicotinic Acid; 4-Aminonicotinic Acid tert-Butyl Carbamate
EINECS	Contact for details

Quality Control

Our 4-Bocamino-Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and detailed Certificates of Analysis (COA) to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.