Description

2-(tert-Butoxycarbonyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylic Acid is a key Boc-protected tryptophan derivative and a vital advanced pharmaceutical intermediate. This compound is essential for the synthesis of complex molecules, offering a protected amine group for selective reactions. It is primarily required by pharmaceutical R&D and manufacturing sectors for the development of active pharmaceutical ingredients (APIs), particularly in neurological and psychiatric drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex alkaloids and tryptamine-based Active Pharmaceutical Ingredients (APIs).
• Neurological Drug Research: Used in the development of compounds targeting serotonin and melatonin receptors for treating depression, anxiety, and sleep disorders.
• Peptide Synthesis: Serves as a protected amino acid analog for the solid-phase and solution-phase synthesis of bioactive peptides.
• Organic Synthesis: Employed as a versatile intermediate in multi-step synthetic routes for natural product synthesis and medicinal chemistry.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory research in heterocyclic chemistry.

Basic Information

Product Name	2-(tert-Butoxycarbonyl)-2,3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indole-3-Carboxylic Acid
CAS No.	171047-77-1
Molecular Formula	C₁₇H₂₀N₂O₄
Molecular Weight	316.35 g/mol
Synonyms	Boc-Tryptoline-3-carboxylic Acid; 1-Boc-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic Acid; Boc-THβC-3-COOH; (3S)-1,2,3,4-Tetrahydro-1-[(2-methylpropan-2-yl)oxycarbonyl]-9H-pyrido[3,4-b]indole-3-carboxylic Acid; 1-Boc-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic Acid; 2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic Acid; Boc-β-Carboline-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. We provide comprehensive analytical data, including HPLC purity, chiral purity (where applicable), and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for all critical parameters to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.