Description

Benzoic Acid, 4-(3-Hydroxy-2-Methylpropyl)-, Methyl Ester, (R)- (9Ci) is a high-purity, single-enantiomer chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of optically active pharmaceuticals and fine chemicals, where stereochemical purity is critical for efficacy and safety. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chiral motifs into complex target molecules.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and production of active pharmaceutical ingredients (APIs), particularly in stereoselective synthesis.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators where biological activity is stereospecific.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Manufacturing: Employed in the synthesis of complex fragrance and flavor compounds requiring specific optical activity.
• Academic and Industrial R&D: A valuable reference standard and starting material for methodological development in organic and medicinal chemistry.
• Material Science Research: Potential monomer or modifier for creating chiral polymers and advanced functional materials.

Basic Information

Product Name	Benzoic Acid, 4-(3-Hydroxy-2-Methylpropyl)-, Methyl Ester, (R)- (9Ci)
CAS No.	170955-23-4
Molecular Formula	C13H18O3
Molecular Weight	222.28 g/mol
Synonyms	(R)-Methyl 4-(3-hydroxy-2-methylpropyl)benzoate; Methyl (R)-4-(3-hydroxy-2-methylpropyl)benzoate; (R)-Benzoic acid, 4-(3-hydroxy-2-methylpropyl)-, methyl ester; (R)-4-(3-Hydroxy-2-methylpropyl)benzoic acid methyl ester; (R)-HMBE; (R)-Methyl 4-(3-hydroxy-2-methylpropyl)benzoic acid ester; (R)-enantiomer of CAS 170955-23-4
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-(3-Hydroxy-2-Methylpropyl)-, Methyl Ester, (R)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.