Description

4-Amino-3-Hydroxy Butanoic Acid Methyl Ester Hydrochloride is a high-purity, pharmaceutically relevant chiral building block. This compound is a crucial synthetic intermediate for the production of advanced active pharmaceutical ingredients (APIs), particularly in the development of neurological and cardiovascular therapeutics. It is essential for research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of GABA (γ-aminobutyric acid) analogs and other neuroactive compounds.
• API Synthesis: Used in the production route for drugs targeting neurological disorders, such as certain antiepileptics and neuroprotectants.
• Asymmetric Synthesis: Serves as a valuable starting material for the preparation of enantiomerically pure compounds due to its defined stereochemistry.
• Peptidomimetics Research: Employed in the design and synthesis of peptide-like molecules for drug discovery programs.
• Bioconjugation Chemistry: The functional groups allow for its use in creating chemical linkages in bioconjugate and prodrug development.
• Chemical Reference Standard: Used as a high-purity standard in analytical method development and quality control laboratories.

Basic Information

Product Name	4-Amino-3-Hydroxy Butanoic Acid Methyl Ester Hydrochloride
CAS No.	170726-96-2
Molecular Formula	C5H12ClNO3
Molecular Weight	169.61 g/mol
Synonyms	Methyl 4-Amino-3-hydroxybutanoate Hydrochloride; (R/S)-Methyl 4-Amino-3-hydroxybutyrate Hydrochloride; 3-Hydroxy-4-aminobutanoic Acid Methyl Ester HCl; GABA Methyl Ester Derivative Hydrochloride; Methyl 3-Hydroxy-4-aminobutyrate Hydrochloride; 4-Amino-3-hydroxybutyric Acid Methyl Ester Hydrochloride; ABH Methyl Ester HCl
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Hydroxy Butanoic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination, to ensure it meets the stringent requirements for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment, ensuring full traceability and compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.