Description

5-Chloro-1-Methyl-3-Nitropyridin-2(1H)-One is a high-purity, synthetically valuable heterocyclic building block. This compound is a key intermediate in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its unique substitution pattern enables critical structural modifications. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex nitrogen-containing molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging its nitropyridine core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies.
• Material Science: Potential intermediate for creating functionalized ligands or organic electronic materials.
• Custom Synthesis: Employed in contract manufacturing for the production of bespoke fine chemicals and advanced intermediates.

Basic Information

Product Name	5-Chloro-1-Methyl-3-Nitropyridin-2(1H)-One
CAS No.	170661-48-0
Molecular Formula	C6H5ClN2O3
Molecular Weight	188.57 g/mol
Synonyms	5-Chloro-1-methyl-3-nitro-2(1H)-pyridinone; 5-Chloro-1-methyl-3-nitropyridin-2(1H)-one; 2(1H)-Pyridinone, 5-chloro-1-methyl-3-nitro-; 5-Chloro-1-methyl-3-nitro-1H-pyridin-2-one; 5-Chloro-1-methyl-3-nitropyridin-2-ol; 170661-48-0
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-Methyl-3-Nitropyridin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.