Description

2-Pyridinecarboxylic Acid, 3-Methoxy-4-(2,2,2-Trifluoroethoxy)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine core substituted with methoxy and trifluoroethoxy functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a key building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and commercial synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Serves as a precursor for developing new generation pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Ligand Synthesis: Used in academic and industrial research to create specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the development of advanced organic electronic materials and functional polymers.
• Chemical Biology Probes: Acts as a scaffold for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	2-Pyridinecarboxylic Acid, 3-Methoxy-4-(2,2,2-Trifluoroethoxy)-
CAS No.	170621-84-8
Molecular Formula	C10H10F3NO4
Molecular Weight	265.19 g/mol
Synonyms	3-Methoxy-4-(2,2,2-trifluoroethoxy)picolinic acid; 3-Methoxy-4-(2,2,2-trifluoroethoxy)pyridine-2-carboxylic acid; 4-(2,2,2-Trifluoroethoxy)-3-methoxypicolinic acid; 2-Carboxy-3-methoxy-4-(2,2,2-trifluoroethoxy)pyridine; Picolinic acid, 3-methoxy-4-(2,2,2-trifluoroethoxy)-; 170621-84-8; 3-Methoxy-4-(trifluoroethoxy)-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxylic Acid, 3-Methoxy-4-(2,2,2-Trifluoroethoxy)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specification results. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.