Description

Methyl 6-((tert-Butoxycarbonyl)Amino)Spiro[3.3]Heptane-2-Carboxylate is a high-value, protected amino acid derivative featuring a rigid spiro[3.3]heptane scaffold, which is of significant interest in modern medicinal chemistry. This compound serves as a critical advanced pharmaceutical intermediate (API) for the synthesis of novel drug candidates, particularly in the development of protease inhibitors and other small molecule therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in cutting-edge drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its unique spirocyclic structure that can improve metabolic stability and binding affinity.
• Protease Inhibitor Development: Serves as a core scaffold or precursor in the design of inhibitors for enzymes like proteases, which are targets for antiviral, anticancer, and anti-inflammatory drugs.
• Peptidomimetics: Employed in the creation of peptidomimetic compounds, where the spiro[3.3]heptane group acts as a conformationally restricted surrogate for amino acid side chains.
• Chemical Biology Probes: Utilized in the development of chemical probes to study biological processes and protein function.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing custom synthesis for client-specific drug discovery projects.

Basic Information

Product Name	Methyl 6-((tert-Butoxycarbonyl)Amino)Spiro[3.3]Heptane-2-Carboxylate
CAS No.	170508-14-2
Molecular Formula	C15H25NO4
Molecular Weight	283.36 g/mol
Synonyms	Methyl 6-((tert-butoxycarbonyl)amino)spiro[3.3]heptane-2-carboxylate; 6-((tert-Butoxycarbonyl)amino)spiro[3.3]heptane-2-carboxylic acid methyl ester; Boc-6-amino-spiro[3.3]heptane-2-carboxylic acid methyl ester; (Spiro[3.3]heptane-2-carboxylic acid, 6-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester); Methyl 6-(Boc-amino)spiro[3.3]heptane-2-carboxylate; Boc-Amino-Spiro[3.3]heptane-COOMe; 170508-14-2; Spirocyclic Boc-protected amino ester
EINECS	Contact for details

Quality Control

Our production of Methyl 6-((tert-Butoxycarbonyl)Amino)Spiro[3.3]Heptane-2-Carboxylate adheres to stringent quality protocols suitable for pharmaceutical R&D. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep away from strong acids and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.