Description

2-Pyridinesulfonylacetonitrile is a versatile and high-value organic building block characterized by its reactive sulfonyl and nitrile functional groups attached to a pyridine ring. This compound is of significant importance in advanced organic synthesis, particularly for constructing complex heterocyclic scaffolds and pharmaceutical intermediates. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, polymers, and advanced functional materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and protein functions.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical reactions in synthetic organic chemistry laboratories.

Basic Information

Product Name	2-Pyridinesulfonylacetonitrile
CAS No.	170449-34-0
Molecular Formula	C7H6N2O2S
Molecular Weight	182.20 g/mol
Synonyms	2-Pyridylsulfonylacetonitrile; (Pyridin-2-ylsulfonyl)acetonitrile; Acetonitrile, 2-pyridinylsulfonyl-; 2-Pyridinesulfonyl Acetonitrile; Pyridine-2-sulfonylacetonitrile; 2-Pyridylsulfonylacetonitrile; 2-Pyridinesulfonyl cyanomethane
EINECS	Contact for details

Quality Control

Our 2-Pyridinesulfonylacetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.