Description

3-Pyridinecarboxaldehyde, 1,4,5,6-Tetrahydro-6-Hydroxy-1-Methyl- (9Ci) is a specialized heterocyclic aldehyde building block of significant interest in advanced organic synthesis. Its unique fused-ring structure containing both aldehyde and hydroxyl functional groups makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Used to synthesize complex chelating ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and Industrial Research: A valuable tool for methodological studies in organic chemistry, including new cyclization and functionalization reactions.

Basic Information

Product Name	3-Pyridinecarboxaldehyde, 1,4,5,6-Tetrahydro-6-Hydroxy-1-Methyl- (9Ci)
CAS No.	170232-98-1
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	1-Methyl-1,4,5,6-tetrahydro-6-hydroxy-3-pyridinecarboxaldehyde; 6-Hydroxy-1-methyl-1,4,5,6-tetrahydro-3-pyridinecarboxaldehyde; 1-Methyl-6-hydroxy-1,2,3,4-tetrahydro-3-pyridinecarbaldehyde; (6-Hydroxy-1-methyl-1,4,5,6-tetrahydropyridin-3-yl)methanol (tautomer); 3-Formyl-1-methyl-1,4,5,6-tetrahydro-6-hydroxypyridine
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxaldehyde, 1,4,5,6-Tetrahydro-6-Hydroxy-1-Methyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers must be sealed immediately after use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.