Description

3-(tert-Butoxycarbonyl)-3-Azaspiro[5.5]Undecane-9-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and Boc-protected amine structure. This compound is critical for synthesizing complex molecules where precise stereochemistry and functional group protection are required. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS).
• Organic Synthesis Reagent: Used in research and development for constructing spirocyclic frameworks and introducing protected amine functionalities.
• Peptidomimetics & PROTACs: Serves as a crucial component in the design and synthesis of peptide mimics and proteolysis-targeting chimeras (PROTACs).
• Agrochemical Research: Employed in the discovery and development of new agrochemicals with specific biological activity.
• Material Science: Potential use as a monomer or precursor for specialty polymers and advanced materials.

Basic Information

Product Name	3-(tert-Butoxycarbonyl)-3-Azaspiro[5.5]Undecane-9-Carboxylic Acid
CAS No.	170228-81-6
Molecular Formula	C15H25NO4
Molecular Weight	283.36 g/mol
Synonyms	3-[(tert-Butoxy)carbonyl]-3-azaspiro[5.5]undecane-9-carboxylic acid; 3-Boc-3-azaspiro[5.5]undecane-9-carboxylic acid; 3-Azaspiro[5.5]undecane-9-carboxylic acid, 3-[(1,1-dimethylethoxy)carbonyl]-; 9-Carboxy-3-Boc-3-azaspiro[5.5]undecane; Boc-3-aza-spiro[5.5]undecane-9-carboxylic acid; 170228-81-6; 3-(Boc)-3-azaspiro[5.5]undecane-9-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(tert-Butoxycarbonyl)-3-Azaspiro[5.5]Undecane-9-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.