Description

Boc-L-4-Aminomethylphenylalanine(Fmoc) is a protected amino acid derivative of significant importance in modern peptide synthesis. This compound, with CAS number 170157-61-6, is a critical building block designed for the solid-phase synthesis of complex peptides and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, development of therapeutic peptides, and chemical biology studies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential assembly of peptides, particularly in Fmoc-based strategies.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics, including hormone analogs and enzyme inhibitors.
• Peptidomimetic Design: Enables the incorporation of non-natural amino acid side chains to enhance the stability, bioavailability, and activity of peptide leads.
• Chemical Biology Probes: Serves as a building block for creating labeled or modified peptides used to study protein-protein interactions and biological pathways.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.

Basic Information

Product Name	Boc-L-4-Aminomethylphenylalanine(Fmoc)
CAS No.	170157-61-6
Molecular Formula	C26H32N2O6
Molecular Weight	468.55 g/mol
Synonyms	Boc-Amp(Fmoc)-OH; N-α-Boc-N-ε-Fmoc-L-4-Aminomethylphenylalanine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-((tert-butoxycarbonyl)amino)methyl)phenyl)propanoic acid; Fmoc-L-4-(Boc-amino)methyl)Phe-OH; Boc-L-Phe(4-CH2NHBoc)-OH (Fmoc); tert-Butyloxycarbonyl-L-4-aminomethylphenylalanine (N-ε-Fmoc); Boc-L-4-(N-Fmoc-aminomethyl)phenylalanine
EINECS	Contact for details

Quality Control

Our Boc-L-4-Aminomethylphenylalanine(Fmoc) is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to industry best practices, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Optical Rotation	-15.0° to -20.0° (c=1 in DMF)
Chiral Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.