Description

4-Pyridinepropanoicacid,-α--Amino-2-Cyano-,(S)-(9Ci) is a high-purity, single-enantiomer chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where stereochemical control is paramount. Pharmaceutical research and development teams, as well as specialty chemical manufacturers, need this material to create novel compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Asymmetric Synthesis: Serves as a versatile building block in catalytic asymmetric reactions to construct complex molecular architectures.
• Agrochemical Research: Used in the development of new, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for metal-catalyzed transformations and organocatalysts.
• Peptidomimetics and Bioactive Molecule Synthesis: The amino acid-like structure makes it valuable for creating peptide analogs and other biologically active molecules.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	4-Pyridinepropanoicacid,-α--Amino-2-Cyano-,(S)-(9Ci)
CAS No.	169949-53-5
Molecular Formula	C9H9N3O2
Molecular Weight	191.19 g/mol
Synonyms	(S)-2-Amino-2-cyano-3-(4-pyridyl)propanoic acid; (S)-α-Amino-2-cyano-4-pyridinepropanoic acid; (2S)-2-Amino-2-cyano-3-pyridin-4-ylpropanoic acid; 4-Pyridinepropanoic acid, α-amino-2-cyano-, (S)-; L-2-Amino-2-cyano-3-(4-pyridyl)propionic acid; (S)-2-Cyano-2-amino-3-(4-pyridyl)propionic acid; 169949-53-5; (S)-Amino(cyanomethyl)(4-pyridyl)acetic acid
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up work. Every lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry to confirm identity, enantiomeric excess (ee), and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.