Description

Cyclobutanecarboxylic Acid, 3-Hydroxy-1-Methyl-, Methyl Ester (9Ci) is a specialized chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, high-value molecules, particularly in the pharmaceutical sector. Industries that require precise stereochemistry and functional group manipulation, such as pharmaceutical R&D and fine chemical manufacturing, are the primary users of this material.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders or metabolic diseases.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Agrochemical Research: Employed in the development of novel, biologically active compounds for crop protection and pest management.
• Material Science Precursor: Acts as a monomer or functionalized unit in the research and development of specialized polymers and advanced materials.
• Academic & Industrial R&D: Used in methodological studies and process chemistry development within university laboratories and corporate research centers.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 3-Hydroxy-1-Methyl-, Methyl Ester (9Ci)
CAS No.	169899-49-4
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	Methyl 3-Hydroxy-1-methylcyclobutanecarboxylate; 3-Hydroxy-1-methylcyclobutanecarboxylic acid methyl ester; Methyl 1-methyl-3-hydroxycyclobutanecarboxylate; (1-Methyl-3-hydroxycyclobutyl)carboxylic acid methyl ester; Cyclobutanecarboxylic acid, 3-hydroxy-1-methyl-, methyl ester; 169899-49-4; Methyl 3-hydroxy-1-methylcyclobutane-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of Cyclobutanecarboxylic Acid, 3-Hydroxy-1-Methyl-, Methyl Ester (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, which is critical for sensitive synthetic applications. All materials are supported by comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess (where applicable), and impurity profiles. We are committed to meeting the exacting standards required for pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.