Description

Ethyl 5-Bromo-6-Hydroxynicotinate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Synthesis: Employed for constructing sophisticated ligands used in catalysis and material science.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study biological processes.
• Functional Material Development: A building block for organic electronic materials and advanced polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules.

Basic Information

Product Name	Ethyl 5-Bromo-6-Hydroxynicotinate
CAS No.	169773-94-8
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	5-Bromo-6-hydroxy-3-pyridinecarboxylic acid ethyl ester; Ethyl 5-bromo-6-hydroxy-3-pyridinecarboxylate; 6-Hydroxy-5-bromonicotinic acid ethyl ester; 3-Pyridinecarboxylic acid, 5-bromo-6-hydroxy-, ethyl ester; 5-Bromo-6-hydroxynicotinic acid ethyl ester; Ethyl 5-bromo-6-oxo-1,6-dihydropyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-6-Hydroxynicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.