Description

(4Ar,7As)-Octahydro-1H-Pyrrolo[3,4-B]Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a unique fused bicyclic structure. This compound is a critical chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering significant value in creating molecules with specific stereochemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for stereoselective synthesis.
• Agrochemical Research: Used in the development of novel pesticides and herbicides with enhanced efficacy and selectivity.
• Academic & R&D: A valuable tool for medicinal chemistry research and process development in organic synthesis.
• Custom Synthesis: A starting material for the contract manufacturing of bespoke fine chemicals and proprietary compounds.

Basic Information

Product Name	(4Ar,7As)-Octahydro-1H-Pyrrolo[3,4-B]Pyridine
CAS No.	169533-55-5
Molecular Formula	C7H14N2
Molecular Weight	126.20 g/mol
Synonyms	(4aR,7aS)-Octahydro-1H-pyrrolo[3,4-b]pyridine; (4aR,7aS)-Octahydro-1H-pyrrolo[3,4-b]pyridine; (4aR,7aS)-1,2,3,4,4a,5,7,7a-Octahydropyrrolo[3,4-b]pyridine; (4aR,7aS)-Octahydropyrrolo[3,4-b]pyridine; (4aR,7aS)-Perhydropyrrolo[3,4-b]pyridine; (4aR,7aS)-Hexahydro-1H-pyrrolo[3,4-b]pyridine (common misnomer); Chiral Bicyclic Amine Intermediate
EINECS	Contact for details

Quality Control

Our (4Ar,7As)-Octahydro-1H-Pyrrolo[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.