Description

(S)-1-(Pyridin-4-Ylmethyl)Pyrrolidin-3-Amine Trihydrochloride is a high-purity chiral amine salt with significant utility in advanced pharmaceutical synthesis. This compound serves as a critical building block and chiral intermediate for the development of active pharmaceutical ingredients (APIs), particularly in neurological and receptor-targeted therapies. It is essential for research institutions and pharmaceutical manufacturers engaged in asymmetric synthesis and the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules, particularly for central nervous system (CNS) targets.
• API Development: Used in research and development for constructing the core scaffold of potential new chemical entities (NCEs).
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in medicinal chemistry and biochemical research.
• Asymmetric Catalysis: May be utilized in the preparation of chiral catalysts or auxiliaries for stereoselective transformations.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	(S)-1-(Pyridin-4-Ylmethyl)Pyrrolidin-3-Amine Trihydrochloride
CAS No.	169452-30-6
Molecular Formula	C11H18N3•3HCl
Molecular Weight	307.66 g/mol (free base: 192.28 g/mol)
Synonyms	(S)-1-((Pyridin-4-yl)methyl)pyrrolidin-3-amine trihydrochloride; (S)-3-Amino-1-(4-pyridylmethyl)pyrrolidine trihydrochloride; (S)-1-(4-Pyridylmethyl)-3-aminopyrrolidine trihydrochloride; (S)-1-(Pyridin-4-ylmethyl)pyrrolidin-3-amine hydrochloride (1:3); Pyrrolidin-3-amine, 1-(4-pyridinylmethyl)-, (3S)-, trihydrochloride; (S)-Pyrrolidin-3-amine, 1-(pyridin-4-ylmethyl)-, trihydrochloride
EINECS	Contact for details

Quality Control

Our (S)-1-(Pyridin-4-Ylmethyl)Pyrrolidin-3-Amine Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.