Description

2-Amino-6-Chloro-9H-Purine-9-Acetic Acid Benzyl Ester is a key purine derivative and a versatile chemical intermediate of significant importance in advanced organic synthesis. Its primary value lies in serving as a crucial building block for the development of nucleoside analogs and other biologically active compounds. This high-purity intermediate is essential for research and production in the pharmaceutical and biotechnology sectors, particularly for antiviral and anticancer drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside and nucleotide analogs with potential therapeutic activity.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Oncology Research: Serves as a building block for purine-based compounds being investigated for anticancer properties.
• Biochemical Tool Compound: Employed in enzymatic studies and as a substrate analog to investigate purine metabolism pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs specializing in complex heterocyclic chemistry.
• Agrochemical Intermediate: Potential use in the synthesis of specialized agrochemicals requiring modified purine structures.

Basic Information

Item	Details
Product Name	2-Amino-6-Chloro-9H-Purine-9-Acetic Acid Benzyl Ester
CAS No.	169287-67-6
Molecular Formula	C14H12ClN5O2
Molecular Weight	317.73 g/mol
Synonyms	9H-Purine-9-acetic acid, 2-amino-6-chloro-, phenylmethyl ester; Benzyl 2-amino-6-chloropurine-9-acetate; 2-Amino-6-chloropurine-9-acetic acid benzyl ester; 6-Chloro-2-aminopurine-9-acetic acid benzyl ester; 9-(Benzyloxycarbonylmethyl)-2-amino-6-chloropurine; N2-Amino-6-chloro-9-(carbobenzoxymethyl)purine; ACPA Benzyl Ester
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Chloro-9H-Purine-9-Acetic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.